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CS-W001157 4
Total: USD 88.00

3-(4-Bromo-3-fluoro-phenyl)-propionic acid

  • CAS No. 127425-80-3

  • Cat. No. CS-0059887
  • Molecule weight247.06
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-(4-Bromo-3-fluoro-phenyl)-propionic acid|CS-0059887

Structure of 127425-80-3

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General Information

  • CAS No. 127425-80-3
  • Cat. No. CS-0059887
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈BrFO₂
  • Molecular Weight 247.06
  • Synonym(s) 3-(4-Bromo-3-fluorophenyl)propanoic acid
  • SMILES C=1(C=C(C(=CC1)Br)F)CCC(=O)O

Description

This boronate-bearing compound features a bromo-fluoro-substituted phenyl ring linked to a propionic acid handle, enabling direct integration into Suzuki-Miyaura coupling reactions. The electron-deficient aryl moiety enhances reactivity while maintaining bench-stable handling under standard conditions.

Application

3-(4-Bromo-3-fluorophenyl)propionic acid serves as a valuable building block for the synthesis of bioactive molecules, particularly in medicinal chemistry and pharmaceutical development. Its well-defined aryl halogen substituents enable robust cross-coupling reactions, including Suzuki and Stille transformations. The carboxylic acid functionality facilitates direct derivatization or incorporation into peptide-like scaffolds, while the molecule exhibits good bench stability and ease of purification.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.6054
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   3

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