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Structure of 127406-08-0
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4-(Pyrazin-2-yl)benzaldehyde features a pyrazine ring linked to a benzaldehyde moiety, creating a rigid, electron-deficient scaffold ideal for transition metal-catalyzed coupling reactions. This conjugated system enhances planarity and facilitates π-stacking in supramolecular architectures. The aldehyde group enables direct functionalization via nucleophilic addition or oxime formation, supporting rapid access to bioactive heterocycles and advanced ligands.
4-(Pyrazin-2-yl)benzaldehyde serves as a versatile building block for conjugated heteroaromatic systems, enabling efficient construction of biaryl scaffolds via Suzuki-Miyaura and Ullmann-type coupling reactions. The aldehyde functionality facilitates direct incorporation into imine-based libraries and oxime derivatizations, while the pyrazine ring provides enhanced solubility and metabolic stability. Bench-stable and amenable to standard purification methods, it functions effectively in multi-step synthesis of pharmaceutical intermediates and functional materials.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: