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Structure of 1273651-10-7
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Methyl 6-fluoro-3-oxo-2,3-dihydro-1H-indene-5-carboxylate is a fluorinated heterocyclic ester featuring a conjugated enone system and a strategically positioned fluorine atom. This scaffold delivers enhanced metabolic stability and electron-withdrawing effects, enabling efficient incorporation into complex molecular architectures. The bench-stable, moisture-tolerant reagent integrates readily into synthetic sequences requiring polarizable, electron-deficient aryl motifs.
Methyl 6-fluoro-3-oxo-2,3-dihydro-1H-indene-5-carboxylate serves as a versatile building block in synthetic organic chemistry, enabling the construction of fluorinated indene scaffolds relevant to medicinal chemistry. The molecule combines a ketone, ester, and strategically positioned fluorine substituent, offering enhanced stability and predictable reactivity in nucleophilic additions, enolate chemistry, and transition-metal-catalyzed couplings. Its bench-stable nature and compatibility with standard purification methods facilitate efficient integration into multi-step syntheses.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: