tert-Butyl 4-(6-chloropyridin-2-yl)piperidine-1-carboxylate

Name: tert-Butyl 4-(6-chloropyridin-2-yl)piperidine-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1266118-78-8
Cat. No. CS-0379052
Purity≥98%
MDL No.MFCD18206123

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(6-chloropyridin-2-yl)piperidine-1-carboxylate|CS-0379052

Structure of 1266118-78-8

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1266118-78-8
Cat. No. CS-0379052
Purity ≥98%
MDL No. MFCD18206123
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₅H₂₁ClN₂O₂
Molecular Weight 296.79
Synonym(s) None
SMILES O=C(N1CCC(C2=NC(Cl)=CC=C2)CC1)OC(C)(C)C

Description

tert-Butyl 4-(6-chloropyridin-2-yl)piperidine-1-carboxylate features a chloropyridine moiety linked to a piperidine scaffold, enabling direct incorporation into bioactive molecule synthesis. The tert-butyl ester group provides stability and facilitates straightforward deprotection under mild acidic conditions. This compound serves as a key intermediate in the development of kinase inhibitors and other pharmaceutical agents requiring a polar, electron-deficient heterocyclic core.

Application

tert-Butyl 4-(6-chloropyridin-2-yl)piperidine-1-carboxylate serves as a versatile building block for the synthesis of bioactive heterocycles, enabling direct functionalization at the pyridine ring and piperidine nitrogen. The tert-butyl carbamate group offers excellent bench stability and facile removal under mild acidic conditions. Its compatibility with palladium-catalyzed cross-coupling reactions facilitates efficient construction of complex scaffolds relevant to medicinal chemistry and process development.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 42.43
LogP 3.8495
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Drug Discovery Metabolic Disease GLP-1R

Key Words

1266118-78-8 sigma1266118-78-8 manufacturer1266118-78-8 price1266118-78-8 structure1266118-78-8 SDSbuy 1266118-78-81266118-78-8 supplier1266118-78-8 uses1266118-78-8 molecular weightprice of 1266118-78-81266118-78-8 chemical name formula of 1266118-78-8

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 4-(6-chloropyridin-2-yl)piperidine-1-carboxylate

CAS No. 1266118-78-8

Recommended Products