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CS-W001157 4
Total: USD 88.00

2-Morpholinothiazole-4-carbaldehyde

  • CAS No. 126533-97-9

  • Cat. No. CS-0318642
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-Morpholinothiazole-4-carbaldehyde|CS-0318642

Structure of 126533-97-9

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General Information

  • CAS No. 126533-97-9
  • Cat. No. CS-0318642
  • Purity ≥98%
  • MDL No. None
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₀N₂O₂S
  • Molecular Weight 198.24
  • Synonym(s) 4-(4-Formyl-1,3-thiazol-2-yl)morpholine, 4-Formyl-2-(morpholin-4-yl)-1,3-thiazole
  • SMILES C1COCCN1C2=NC(=CS2)C=O

Description

2-Morpholinothiazole-4-carbaldehyde features a morpholino group attached to a thiazole ring, delivering enhanced solubility and electronic modulation. The aldehyde functionality enables direct coupling in condensation reactions, serving as a key scaffold for bioactive molecule synthesis. This compound exhibits bench-stable handling and compatibility with diverse reaction conditions.

Application

2-Morpholinothiazole-4-carbaldehyde serves as a versatile building block in medicinal chemistry, enabling efficient access to thiazole-based scaffolds through standard functional group transformations. Its aldehyde functionality facilitates reductive amination, Grignard additions, and coupling reactions with nucleophiles, while the morpholino group enhances solubility and modulates electronic properties. The compound exhibits bench stability and compatibility with common protecting groups, supporting its use in multi-step syntheses of bioactive molecules.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H312-H315-H319-H332-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   42.43
  • LogP   0.7922
  • H_Acceptors   5
  • H_Donors   0
  • Rotatable_Bonds   2

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