Benzyl 4-bromobutanoate

Name: Benzyl 4-bromobutanoate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 126430-46-4
Cat. No. CS-W018907
Purity≥97%
MDL No.MFCD00143681

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 126430-46-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 126430-46-4
Cat. No. CS-W018907
Purity ≥97%
MDL No. MFCD00143681
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₁H₁₃BrO₂
Molecular Weight 257.12
Synonym(s) 4-bromobutyric acid benzyl ester
SMILES O=C(OCC1=CC=CC=C1)CCCBr

Description

Benzyl 4-bromobutanoate features a brominated aliphatic chain appended to a benzyl ester moiety, enabling direct incorporation into cross-coupling reactions. The terminal bromide serves as a reactive handle for palladium-catalyzed transformations, while the benzyl group offers stability and ease of removal under mild conditions. This combination delivers efficient access to functionalized carbonyl derivatives in synthetic sequences.

Application

Benzyl 4-bromobutanoate serves as a versatile building block in synthetic organic chemistry, enabling efficient construction of γ-butyrolactones and substituted pyrrolidines via intramolecular cyclization. The bromide functionality facilitates nucleophilic substitution reactions, while the benzyl ester group offers stability and convenient removal under mild hydrogenolysis conditions. Its compatibility with diverse reaction conditions makes it well-suited for applications in medicinal chemistry and process development workflows.

Synthesis

Route1
- In-stock
  
  2623-87-2
- In-stock
  
  100-51-6
- ~98%
- In-stock
  
  126430-46-4
References
- Springer, Jasper; De Cuba, Kimberly R.; Calvet-Vitale, Sandrine; Geenevasen, Jan A. J.; Hermkens, Pedro H. H.; Hiemstra, Henk; Van Maarseveen, Jan H. European Journal of Organic Chemistry, 2008 , # 15 p. 2592 - 2600
Route2
- 927-58-2
- In-stock
  
  100-51-6
- ~83%
- In-stock
  
  126430-46-4
References
- NitroMed, Inc. Patent: US2006/189603 A1, 2006 ; Location in patent: Page/Page column 57 ; US 20060189603 A1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H227-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 26.3
LogP 2.9049
H_Acceptors 2
H_Donors 0
Rotatable_Bonds 5

Other Classifications

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

Benzyl 4-bromobutanoate sigmaBenzyl 4-bromobutanoate manufacturerBenzyl 4-bromobutanoate priceBenzyl 4-bromobutanoate structureBenzyl 4-bromobutanoate SDSbuy Benzyl 4-bromobutanoateBenzyl 4-bromobutanoate supplierBenzyl 4-bromobutanoate usesBenzyl 4-bromobutanoate molecular weightprice of Benzyl 4-bromobutanoateBenzyl 4-bromobutanoate chemical name formula of Benzyl 4-bromobutanoate

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Benzyl 4-bromobutanoate

CAS No. 126430-46-4

Recommended Products