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Structure of 1263378-90-0
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3-Bromo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine features a fused bicyclic core with a bromine substituent at the 3-position, enabling direct functionalization in transition-metal-catalyzed cross-coupling reactions. The saturated pyrazolo[1,5-a]pyrazine scaffold provides enhanced metabolic stability and favorable solubility characteristics for medicinal chemistry applications.
3-Bromo-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine serves as a versatile heterocyclic building block in medicinal chemistry, enabling efficient access to pyrazolo-pyrazine scaffolds via palladium-catalyzed cross-coupling. Its bromo substituent facilitates reliable C–C bond formation under standard Suzuki, Stille, or Negishi conditions, while the saturated core offers enhanced solubility and metabolic stability. The compound exhibits good bench stability and compatibility with diverse functional groups, making it well-suited for modular synthesis of bioactive molecules and API intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: