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Structure of 1263374-32-8
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This aminomethyltetrahydropyran carbonitrile features a pendant nitrile group and a primary amine tethered to a saturated pyran ring, enabling dual functionalization. The rigid tetrahydro-2H-pyran scaffold provides conformational stability, while the amine facilitates coupling reactions. This structure serves as a key intermediate for bioactive molecule synthesis.
4-(Aminomethyl)tetrahydro-2H-pyran-4-carbonitrile serves as a versatile building block in medicinal chemistry, enabling the synthesis of heterocyclic scaffolds through nucleophilic addition and cyclization reactions. The nitrile group facilitates functionalization via hydrolysis or reduction, while the pendant amine supports conjugation and derivatization. Its tetrahydrofuran ring imparts structural rigidity and favorable solubility, enhancing utility in drug discovery campaigns.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: