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Structure of 1262412-13-4
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This azetidine-based scaffold features a tert-butoxycarbonyl-protected amine and a carboxylic acid group, enabling direct incorporation into peptide chains or macrocyclization strategies. The strained azetidine ring imparts conformational rigidity, while the protecting group ensures stability during synthetic manipulations.
3-Amino-1-[(tert-butoxy)carbonyl]azetidine-3-carboxylic acid serves as a versatile building block for the synthesis of azetidinyl-containing bioactive molecules. The tert-butoxycarbonyl (Boc) group provides excellent stability and orthogonal deprotection, enabling efficient incorporation into peptide-like scaffolds. The pendant primary amine and carboxylic acid functionalities facilitate sequential functionalization, supporting diverse coupling reactions and cyclization strategies in medicinal chemistry applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: