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Structure of 1262278-60-3
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trans-3-Fluorocyclobutanol features a strained cyclobutane ring with a fluorine atom and hydroxyl group in trans configuration, delivering enhanced stability and distinct stereochemical control. This bench-stable, moisture-tolerant reagent integrates readily into synthetic pathways requiring stereoselective functionalization or as a building block in medicinal chemistry.
trans-3-Fluorocyclobutanol serves as a valuable chiral building block in medicinal chemistry, offering a rigid cyclobutane scaffold with defined stereochemistry. Its fluorinated ring system enhances metabolic stability and modulates electronic properties, while the hydroxyl group enables straightforward functionalization via esterification, etherification, or oxidation. The compound exhibits excellent bench stability and facilitates efficient incorporation into bioactive molecules through standard coupling and transformation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: