Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(2,3-Difluorophenyl)ethanol

  • CAS No. 126163-30-2

  • Cat. No. CS-0157224
  • Purity≥98%
  • MDL No.MFCD01862011

*For research and further manufacturing use only, not for direct human use.

2-(2,3-Difluorophenyl)ethanol|CS-0157224

Structure of 126163-30-2

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 126163-30-2
  • Cat. No. CS-0157224
  • Purity ≥98%
  • MDL No. MFCD01862011
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₈F₂O
  • Molecular Weight 158.15
  • Synonym(s) None
  • SMILES C1=CC(=C(C(=C1)F)F)CCO

Description

2-(2,3-Difluorophenyl)ethanol features a fluorinated aromatic core that enhances metabolic stability and membrane permeability. This bench-stable alcohol integrates readily into pharmaceutical intermediates, serving as a key scaffold for bioactive molecule synthesis. The para-difluoro substitution pattern imparts favorable electronic and steric properties, enabling efficient coupling reactions under standard conditions.

Application

2-(2,3-Difluorophenyl)ethanol serves as a versatile building block in medicinal chemistry, enabling efficient construction of bioactive scaffolds through standard functional group transformations. Its bench-stable nature and compatibility with common coupling reactions facilitate straightforward incorporation into complex molecules. The difluorophenyl moiety enhances metabolic stability and modulates lipophilicity, making it valuable for optimizing pharmacokinetic profiles in drug discovery campaigns.

Synthesis

  • Route1

    References

    • Takeuchi, Craig S.; Kim, Byung Gyu; Blazey, Charles M.; Ma, Sunghoon; Johnson, Henry W. B.; Anand, Neel K.; Arcalas, Arlyn; Baik, Tae Gon; Buhr, Chris A.; Cannoy, Jonah; Epshteyn, Sergey; Joshi, Anagha; Lara, Katherine; Lee, Matthew S.; Wang, Longcheng; Leahy, James W.; Nuss, John M.; Aay, Naing; Aoyama, Ron; Foster, Paul; Lee, Jae; Lehoux, Isabelle; Munagala, Narsimha; Plonowski, Arthur; Rajan, Sharmila; Woolfrey, John; Yamaguchi, Kyoko; Lamb, Peter; Miller, Nicole Journal of Medicinal Chemistry, 2013 , vol. 56, # 6 p. 2218 - 2234

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   20.23
  • LogP   1.4996
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 2-(2,3-Difluorophenyl)ethanol sigma2-(2,3-Difluorophenyl)ethanol manufacturer2-(2,3-Difluorophenyl)ethanol price2-(2,3-Difluorophenyl)ethanol structure2-(2,3-Difluorophenyl)ethanol SDSbuy 2-(2,3-Difluorophenyl)ethanol2-(2,3-Difluorophenyl)ethanol supplier2-(2,3-Difluorophenyl)ethanol uses2-(2,3-Difluorophenyl)ethanol molecular weightprice of 2-(2,3-Difluorophenyl)ethanol2-(2,3-Difluorophenyl)ethanol chemical name formula of 2-(2,3-Difluorophenyl)ethanol
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label