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(1-Methylcyclopropyl)methanamine hydrochloride

  • CAS No. 1260779-19-8

  • Cat. No. CS-0037189
  • Purity≥95%
  • MDL No.MFCD12962560

*For research and further manufacturing use only, not for direct human use.

(1-Methylcyclopropyl)methanamine hydrochloride|CS-0037189

Structure of 1260779-19-8

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General Information

  • CAS No. 1260779-19-8
  • Cat. No. CS-0037189
  • Purity ≥95%
  • MDL No. MFCD12962560
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₁₂ClN
  • Molecular Weight 121.61
  • Synonym(s) 1-(Aminomethyl)-1-methylcyclopropane Hydrochloride
  • SMILES CC1(CC1)CN.Cl

Description

This bench-stable amine derivative features a sterically hindered cyclopropyl moiety paired with a primary amine functionality, enabling efficient coupling in synthetic transformations. The hydrochloride salt enhances solubility and stability in aqueous and polar organic media, facilitating use in pharmaceutical synthesis and chemical biology applications.

Application

(1-Methylcyclopropyl)methanamine hydrochloride serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive scaffolds through nucleophilic substitution and amine coupling reactions. Its cyclopropyl-containing alkylamine structure provides enhanced metabolic stability and conformational rigidity, advantageous for optimizing pharmacokinetic properties. The hydrochloride salt ensures excellent bench stability, ease of handling, and straightforward purification, making it well-suited for high-throughput synthesis and process-scale applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   26.02
  • LogP   1.167
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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