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5-Bromo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine

  • CAS No. 1260671-35-9

  • Cat. No. CS-0099996
  • Purity≥97%
  • MDL No.MFCD18250826

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine|CS-0099996

Structure of 1260671-35-9

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General Information

  • CAS No. 1260671-35-9
  • Cat. No. CS-0099996
  • Purity ≥97%
  • MDL No. MFCD18250826
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₇BrN₂
  • Molecular Weight 199.05
  • Synonym(s) 5-bromo-1h,2h,3h-pyrrolo[3,2-b]pyridine
  • SMILES BrC1=CC=C(NCC2)C2=N1

Description

5-Bromo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine is a bench-stable heterocyclic scaffold featuring a brominated pyrrolidine core fused to a pyridine ring. This electron-deficient system enables direct functionalization via palladium-catalyzed cross-coupling, serving as a key building block in medicinal chemistry and materials science.

Application

5-Bromo-2,3-dihydro-1H-pyrrolo[3,2-b]pyridine serves as a versatile building block for the synthesis of bioactive heterocycles, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine handle. The dihydropyrrolopyridine core exhibits favorable bench stability and functional group tolerance, facilitating downstream modifications in medicinal chemistry and materials science applications.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   1.8121
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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