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(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid

  • CAS No. 1260616-69-0

  • Cat. No. CS-0169353
  • Purity≥95%
  • MDL No.MFCD07372099

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid|CS-0169353

Structure of 1260616-69-0

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General Information

  • CAS No. 1260616-69-0
  • Cat. No. CS-0169353
  • Purity ≥95%
  • MDL No. MFCD07372099
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₃₀H₂₅NO₄
  • Molecular Weight 463.52
  • Synonym(s) None
  • SMILES OC([C@H](CC1=CC(C2=CC=CC=C2)=CC=C1)NC(OCC3C4=CC=CC=C4C5=CC=CC=C53)=O)=O

Description

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid is a chiral building block featuring a fluorenylmethoxycarbonyl (Fmoc) protecting group and a biphenyl-substituted alanine scaffold. This configuration enables direct incorporation into peptide synthesis workflows, offering enhanced solubility and stability under standard conditions.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-([1,1'-biphenyl]-3-yl)propanoic acid serves as a valuable chiral building block for peptide synthesis, enabling efficient incorporation of sterically hindered arylalanine derivatives. The Fmoc group provides orthogonal protection and facile removal under mild basic conditions, while the biphenyl moiety imparts metabolic stability and structural rigidity. Bench-stable and compatible with standard coupling protocols, this amino acid derivative facilitates the construction of complex peptidomimetics and biologically active scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362+P364

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   5.888
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   7

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