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CS-W001157 4
Total: USD 88.00

Ethyl 4-bromooxazole-5-carboxylate

  • CAS No. 1258283-17-8

  • Cat. No. CS-W005725
  • Purity≥97%
  • MDL No.MFCD20260216

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-bromooxazole-5-carboxylate|CS-W005725

Structure of 1258283-17-8

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General Information

  • CAS No. 1258283-17-8
  • Cat. No. CS-W005725
  • Purity ≥97%
  • MDL No. MFCD20260216
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BrNO₃
  • Molecular Weight 220.02
  • Synonym(s) None
  • SMILES O=C(C1=C(Br)N=CO1)OCC

Description

Ethyl 4-bromooxazole-5-carboxylate features a brominated oxazole core paired with an ester functionality, enabling direct incorporation into heterocyclic synthesis. This bench-stable reagent facilitates transition-metal-catalyzed couplings and serves as a key intermediate in medicinal chemistry.

Application

Ethyl 4-bromooxazole-5-carboxylate serves as a versatile building block in heterocyclic synthesis, enabling palladium-catalyzed cross-coupling reactions due to its well-defined bromine substituent. The oxazole core provides metabolic stability and structural rigidity, while the ester group offers handle for further derivatization. This compound exhibits excellent bench stability, facilitates straightforward purification, and functions reliably in standard coupling protocols, making it a practical choice for medicinal chemistry and process development workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   52.33
  • LogP   1.6138
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   2

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