Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

Tert-butyl (2-oxo-2-((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)ethyl)carbamate

  • CAS No. 1257651-17-4

  • Cat. No. CS-0174281
  • Molecule weight376.25
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Tert-butyl (2-oxo-2-((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)ethyl)carbamate|CS-0174281

Structure of 1257651-17-4

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1257651-17-4
  • Cat. No. CS-0174281
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₂₉BN₂O₅
  • Molecular Weight 376.25
  • Synonym(s) {[3-(4,4,5,5-Tetramethyl-[1,3,2]dioxaborolan-2-yl)-phenylcarbamoyl]-methyl}-carbamic acid tert-butyl ester
  • SMILES CC(OC(NCC(NC1=CC=CC(B2OC(C(O2)(C)C)(C)C)=C1)=O)=O)(C)C

Description

Tert-butyl (2-oxo-2-((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)ethyl)carbamate is a bench-stable boronate ester bearing a para-aminoaryl handle, enabling direct coupling in Suzuki-Miyaura reactions. This carbamate-protected scaffold integrates seamlessly into peptide and heterocyclic scaffolds under standard conditions, delivering high functional group tolerance and minimal decomposition during purification workflows.

Application

Tert-butyl (2-oxo-2-((3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)amino)ethyl)carbamate serves as a stable, bench-ready boron-containing building block for Suzuki-Miyaura cross-coupling reactions. The dioxaborolane moiety enables efficient coupling with aryl and heteroaryl halides under mild conditions, while the tert-butyl carbamate group provides orthogonal protection for primary amines. Its functional group tolerance and compatibility with standard reaction protocols make it ideal for constructing complex scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302
Precautionary Statements : P264-P270-P330-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   85.89
  • LogP   2.449
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   4

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1257651-17-4 sigma1257651-17-4 manufacturer1257651-17-4 price1257651-17-4 structure1257651-17-4 SDSbuy 1257651-17-41257651-17-4 supplier1257651-17-4 uses1257651-17-4 molecular weightprice of 1257651-17-41257651-17-4 chemical name formula of 1257651-17-4
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label