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Structure of 1256820-00-4
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2-Bromo-5-chloro-3-(trifluoromethyl)pyridine is a halogenated pyridine derivative featuring orthogonal reactivity at bromo and chloro sites. The trifluoromethyl group imparts enhanced electron-withdrawing character and metabolic stability, enabling efficient cross-coupling transformations. This compound serves as a key building block in pharmaceutical synthesis, particularly for heterocyclic scaffolds requiring precise substitution patterns.
2-Bromo-5-chloro-3-(trifluoromethyl)pyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the bromo and chloro substituents allow sequential functionalization. Bench-stable and compatible with standard synthetic workflows, it facilitates the construction of complex heterocyclic scaffolds found in pharmaceutical development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: