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Structure of 1256811-48-9
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2-Chloro-3-methoxyisonicotinonitrile features a strategically positioned nitrile group flanked by chlorine and methoxy substituents on a pyridine core, enabling selective functionalization in heterocyclic synthesis. This electron-deficient scaffold integrates readily into pharmaceutical intermediates and advanced materials, offering enhanced reactivity under mild conditions.
2-Chloro-3-methoxyisonicotinonitrile serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based heterocycles. Its ortho-chloro and nitrile groups facilitate palladium-catalyzed cross-coupling reactions, while the methoxy substituent enhances solubility and modulates electronic properties. The compound exhibits good bench stability and compatibility with standard purification methods, making it well-suited for iterative synthesis workflows targeting bioactive scaffolds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: