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CS-W001157 4
Total: USD 88.00

4-Bromo-6-methylpyridin-3-ol

  • CAS No. 1256811-26-3

  • Cat. No. CS-0120382
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4-Bromo-6-methylpyridin-3-ol|CS-0120382

Structure of 1256811-26-3

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General Information

  • CAS No. 1256811-26-3
  • Cat. No. CS-0120382
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₆BrNO
  • Molecular Weight 188.02
  • Synonym(s) 4-bromo-6-methyl-pyridin-3-ol
  • SMILES OC1=C(Br)C=C(C)N=C1

Description

4-Bromo-6-methylpyridin-3-ol features a pyridinol core with bromine and methyl substituents at meta and para positions, respectively. This electron-deficient heterocycle integrates readily into cross-coupling reactions, offering stable access to functionalized pyridine scaffolds under standard conditions.

Application

4-Bromo-6-methylpyridin-3-ol serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its bromo substituent and electron-rich pyridine core. The phenolic hydroxyl group provides a handle for derivatization, while the methyl group enhances regioselectivity in subsequent functionalizations. This compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis of heterocyclic scaffolds and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   33.12
  • LogP   1.85812
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   0

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