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Structure of 1256794-12-3
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Methyl 3-amino-6-(trifluoromethyl)picolinate features a trifluoromethyl group enhancing electron-withdrawal and metabolic stability, paired with a primary amine enabling facile derivatization. This bench-stable heterocycle integrates readily into medicinal chemistry libraries, serving as a key intermediate for bioactive compound synthesis.
Methyl 3-amino-6-(trifluoromethyl)picolinate serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and API intermediates. The trifluoromethyl group imparts enhanced metabolic stability and lipophilicity, while the amino and ester functionalities offer orthogonal reactivity for downstream derivatization via amidation, acylation, or cyclization reactions. Bench-stable and amenable to standard purification techniques, it functions effectively in multi-step syntheses requiring functional group compatibility and predictable reactivity.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: