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Structure of 1256789-63-5
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3-Bromo-6-fluoro-2-methoxypyridine features a strategically positioned bromo and fluoro substituent on a pyridine core, enabling selective cross-coupling reactions. The methoxy group enhances solubility and modulates electronic properties, while the halogen pattern supports palladium-catalyzed transformations under standard conditions. This bench-stable reagent integrates efficiently into complex molecular architectures.
3-Bromo-6-fluoro-2-methoxypyridine serves as a versatile building block in medicinal chemistry, enabling palladium-catalyzed cross-coupling reactions due to its orthogonal halogen reactivity. The bromo group facilitates Suzuki, Stille, and Negishi couplings, while the fluorine and methoxy substituents provide tunable electronic effects and steric control. Its bench-stable nature and compatibility with diverse reaction conditions make it ideal for constructing functionalized pyridine scaffolds in API development and agrochemical synthesis.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H312-H315-H319-H332-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: