Methyl 5-bromo-6-chloro-2-methylnicotinate

Name: Methyl 5-bromo-6-chloro-2-methylnicotinate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1256788-63-2
Cat. No. CS-0568355
Purity≥95%
MDL No.MFCD18258694

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Methyl 5-bromo-6-chloro-2-methylnicotinate|CS-0568355

Structure of 1256788-63-2

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1256788-63-2
Cat. No. CS-0568355
Purity ≥95%
MDL No. MFCD18258694
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₇BrClNO₂
Molecular Weight None
Synonym(s) 3-Pyridinecarboxylic acid, 5-broMo-6-chloro-2-Methyl-, Methyl ester
SMILES O=C(C1=CC(Br)=C(Cl)N=C1C)OC

Description

Methyl 5-bromo-6-chloro-2-methylnicotinate features a densely functionalized pyridine core with orthogonal halogen handles at C5 (bromo) and C6 (chloro), enabling selective cross-coupling. The methyl group at C2 enhances solubility and modulates electronic properties, while the ester moiety provides a handle for downstream transformations. This compound serves as a key building block in synthetic routes to bioactive heterocycles and pharmaceutical intermediates.

Application

Methyl 5-bromo-6-chloro-2-methylnicotinate serves as a versatile building block in heterocyclic synthesis, enabling regioselective functionalization at the C5 and C6 positions. The bromo and chloro substituents facilitate palladium-catalyzed cross-coupling reactions, while the methyl ester group supports further transformations such as hydrolysis or reduction. Its bench-stable nature and compatibility with standard reaction conditions make it well-suited for medicinal chemistry and process development workflows.

Safety Information

Download SDS

GHS Pictogram : N/A	GHS No : N/A
Signal Word : N/A	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : N/A
Precautionary Statements : N/A

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 39.19
LogP 2.59252
H_Acceptors 3
H_Donors 0
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Bromide

Building Blocks Functional Group Ester

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

1256788-63-2 sigma1256788-63-2 manufacturer1256788-63-2 price1256788-63-2 structure1256788-63-2 SDSbuy 1256788-63-21256788-63-2 supplier1256788-63-2 uses1256788-63-2 molecular weightprice of 1256788-63-21256788-63-2 chemical name formula of 1256788-63-2

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

Methyl 5-bromo-6-chloro-2-methylnicotinate

CAS No. 1256788-63-2

Recommended Products