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Structure of 1254473-66-9
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1-(3,5-Dichloropyridin-4-yl)ethanol features a pyridine core substituted with two chlorine atoms at the 3 and 5 positions, enhancing electron deficiency and enabling robust coupling in cross-coupling reactions. The terminal ethanol group provides solubility and handles cleanly under standard conditions, facilitating integration into synthetic intermediates for pharmaceutical and agrochemical development.
1-(3,5-Dichloropyridin-4-yl)ethanol serves as a versatile building block in medicinal chemistry, enabling efficient construction of pyridine-based scaffolds. Its benzylic alcohol functionality facilitates straightforward derivatization via etherification, esterification, or oxidation to the corresponding aldehyde. The 3,5-dichloro substitution pattern enhances electrophilicity at C4 and provides orthogonal reactivity for cross-coupling processes. Bench-stable and readily purified by distillation or chromatography, it functions effectively in standard synthetic workflows requiring halogenated heterocyclic intermediates.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: