(R)-1-(4-Chloro-3-fluorophenyl)ethan-1-amine hydrochloride

Name: (R)-1-(4-Chloro-3-fluorophenyl)ethan-1-amine hydrochloride
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1253790-80-5
Cat. No. CS-0131600
Purity≥97%
MDL No.MFCD12547495

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(R)-1-(4-Chloro-3-fluorophenyl)ethan-1-amine hydrochloride|CS-0131600

Structure of 1253790-80-5

Size

Price

Quantity

* Please select Quantity before adding items.

Description

This bench-stable chiral amine features a (R)-configured stereocenter adjacent to a 4-chloro-3-fluorophenyl group, delivering high enantiomeric purity. The hydrochloride salt enhances solubility and handling stability, enabling efficient integration into asymmetric synthesis workflows for pharmaceutical intermediates.

Application

(R)-1-(4-Chloro-3-fluorophenyl)ethan-1-amine hydrochloride serves as a chiral building block for the synthesis of bioactive molecules, particularly in medicinal chemistry and API development. Its well-defined stereochemistry enables consistent enantioselective transformations. The compound exhibits good bench stability, ease of handling, and compatibility with standard amine functional group manipulations, including acylation, alkylation, and coupling reactions. It functions as a key intermediate in constructing arylalkylamine motifs found in pharmaceutical scaffolds.

General Information

CAS No. 1253790-80-5
Cat. No. CS-0131600
Purity ≥97%
MDL No. MFCD12547495
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₀Cl₂FN
Molecular Weight 210.08
Synonym(s) (R)-1-(4-Chloro-3-fluorophenyl)-ethanamine hydrochloride
SMILES [H]Cl.ClC1=C(F)C=C([C@H](N)C)C=C1

Computational Chemistry Data

TPSA 26.02
LogP 2.9206
H_Acceptors 1
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

1253790-80-5 sigma1253790-80-5 manufacturer1253790-80-5 price1253790-80-5 structure1253790-80-5 SDSbuy 1253790-80-51253790-80-5 supplier1253790-80-5 uses1253790-80-5 molecular weightprice of 1253790-80-51253790-80-5 chemical name formula of 1253790-80-5

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(R)-1-(4-Chloro-3-fluorophenyl)ethan-1-amine hydrochloride

CAS No. 1253790-80-5

Recommended Products