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Structure of 1251023-52-5
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5-Bromo-2-methyl-2H-indazole-3-carbaldehyde features a brominated indazole core with a methyl group at the 2-position and a formyl substituent at the 3-position. This electron-deficient scaffold enables direct coupling in transition-metal-catalyzed reactions, serving as a key building block for bioactive heterocycles and pharmaceutical intermediates.
5-Bromo-2-methyl-2H-indazole-3-carbaldehyde serves as a versatile building block for heterocyclic synthesis, enabling efficient access to indazole-based scaffolds through palladium-catalyzed coupling reactions. The aldehyde functionality facilitates direct derivatization via reductive amination or Wittig-type transformations, while the bromo and methyl groups offer orthogonal handles for further functionalization. Bench-stable and readily purified by flash chromatography, it functions reliably in medicinal chemistry campaigns targeting kinase inhibitors and CNS-active compounds.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: