tert-Butyl 1,6-diazaspiro[3.5]nonane-1-carboxylate

Name: tert-Butyl 1,6-diazaspiro[3.5]nonane-1-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1251005-45-4
Cat. No. CS-0048491
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 1,6-diazaspiro[3.5]nonane-1-carboxylate|CS-0048491

Structure of 1251005-45-4

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1251005-45-4
Cat. No. CS-0048491
Purity ≥97%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₂H₂₂N₂O₂
Molecular Weight 226.32
Synonym(s) 1-Boc-1,6-diaza-spiro[3.5]nonane
SMILES CC(C)(C)OC(=O)N1CCC11CCCNC1

Description

tert-Butyl 1,6-diazaspiro[3.5]nonane-1-carboxylate features a rigid spirocyclic scaffold with two nitrogen atoms at the 1- and 6-positions, offering enhanced conformational control. The tert-butyl ester group provides stability and ease of handling, enabling straightforward deprotection under mild acidic conditions. This compound serves as a valuable building block in medicinal chemistry for constructing constrained heterocyclic motifs.

Application

tert-Butyl 1,6-diazaspiro[3.5]nonane-1-carboxylate serves as a versatile scaffold for constructing spirocyclic amine libraries, enabling efficient access to constrained piperazine analogs. The tert-butyl carbamate group offers excellent bench stability and facilitates straightforward deprotection under mild acidic conditions. Its dual nitrogen atoms provide orthogonal reactivity for selective functionalization, making it well-suited for medicinal chemistry campaigns targeting CNS-directed therapeutics and kinase inhibitors.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 41.57
LogP 1.7494
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Skeleton Aliphatic heterocycle compounds Piperidine compounds

Building Blocks Skeleton Aliphatic heterocycle compounds Azetidine compounds

Key Words

1251005-45-4 sigma1251005-45-4 manufacturer1251005-45-4 price1251005-45-4 structure1251005-45-4 SDSbuy 1251005-45-41251005-45-4 supplier1251005-45-4 uses1251005-45-4 molecular weightprice of 1251005-45-41251005-45-4 chemical name formula of 1251005-45-4

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 1,6-diazaspiro[3.5]nonane-1-carboxylate

CAS No. 1251005-45-4

Recommended Products