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CS-W001157 4
Total: USD 88.00

1-(2,4,6-Trifluorophenyl)ethanol

  • CAS No. 1250113-83-7

  • Cat. No. CS-0162744
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

1-(2,4,6-Trifluorophenyl)ethanol|CS-0162744

Structure of 1250113-83-7

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General Information

  • CAS No. 1250113-83-7
  • Cat. No. CS-0162744
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇F₃O
  • Molecular Weight 176.14
  • Synonym(s) 1-(2,4,6-trifluorophenyl)ethan-1-ol
  • SMILES CC(O)C1=C(F)C=C(F)C=C1F

Description

1-(2,4,6-Trifluorophenyl)ethanol features a trifluorophenyl group that imparts enhanced metabolic stability and lipophilicity. This bench-stable alcohol integrates readily into pharmaceutical intermediates and functional materials, offering predictable reactivity under standard conditions. The para-fluorine substitution enhances electron-withdrawing character, enabling controlled coupling in synthetic sequences.

Application

1-(2,4,6-Trifluorophenyl)ethanol serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated aryl motifs found in bioactive molecules. Its bench-stable nature and tolerance to common functional groups facilitate straightforward incorporation into diverse scaffolds. The molecule reacts efficiently in standard coupling and oxidation protocols, supporting applications in API development and target-oriented synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   20.23
  • LogP   2.1572
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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