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CS-W001157 4
Total: USD 88.00

Tert-butyl N-(2-aminoethyl)-N-cyclopropylcarbamate

  • CAS No. 1247174-47-5

  • Cat. No. CS-0253613
  • Purity≥97%
  • MDL No.MFCD14627790

*For research and further manufacturing use only, not for direct human use.

Tert-butyl N-(2-aminoethyl)-N-cyclopropylcarbamate|CS-0253613

Structure of 1247174-47-5

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General Information

  • CAS No. 1247174-47-5
  • Cat. No. CS-0253613
  • Purity ≥97%
  • MDL No. MFCD14627790
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂O₂
  • Molecular Weight 200.28
  • Synonym(s) tert-butyl (2-aminoethyl)(cyclopropyl)carbamate
  • SMILES O=C(OC(C)(C)C)N(CCN)C1CC1

Description

Tert-butyl N-(2-aminoethyl)-N-cyclopropylcarbamate features a cyclopropyl group that imparts conformational rigidity, enhancing target selectivity in bioactive molecule design. The tert-butyl carbamate moiety provides stable protection for primary amines under standard conditions, enabling efficient incorporation into peptidomimetics and drug candidates through straightforward deprotection protocols.

Application

Tert-butyl N-(2-aminoethyl)-N-cyclopropylcarbamate serves as a versatile bifunctional building block in medicinal chemistry, enabling efficient synthesis of constrained aminoether scaffolds. The cyclopropyl group imparts conformational rigidity, while the tert-butyl carbamate offers orthogonal protection for primary amines. This compound facilitates straightforward deprotection and coupling reactions, supporting applications in peptide mimicry, CNS-targeted drug discovery, and macrocyclic scaffold construction.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 2733
Class : 3,8
Packing Group : Ⅲ
Hazard Statements : H318-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   1.3446
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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