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CS-W001157 4
Total: USD 88.00

2-Fluoro-4-iodobenzoic acid

  • CAS No. 124700-40-9

  • Cat. No. CS-W002999
  • Purity≥97%
  • MDL No.MFCD03094173

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-4-iodobenzoic acid|CS-W002999

Structure of 124700-40-9

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General Information

  • CAS No. 124700-40-9
  • Cat. No. CS-W002999
  • Purity ≥97%
  • MDL No. MFCD03094173
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₄FIO₂
  • Molecular Weight 266.01
  • Synonym(s) None
  • SMILES FC1=C(C(O)=O)C=CC(I)=C1

Description

2-Fluoro-4-iodobenzoic acid features a strategically positioned fluorine and iodine substituent on the aromatic ring, enabling directed functionalization via cross-coupling. The carboxylic acid group provides a handle for derivatization, while the electron-withdrawing fluorine enhances reactivity in palladium-catalyzed transformations. This compound serves as a key building block for bioactive molecules and advanced materials.

Synthesis

  • Route1

    References

    • SANOFI; BRAUN, Alain; DUCLOS, Olivier; LASSALLE, Gilbert; LORGE, Franz; MARTIN, Valerie; RITZELER, Olaf; STRUB, Aurelie Patent: WO2012/159959 A1, 2012 ; Location in patent: Page/Page column 31 ; WO 2012/159959 A1
  • Route2
    • null|null
      124-38-9
    • In-stock
      2-Fluoro-1,4-diiodobenzene|CS-0157066
      147808-02-4
    • ~98%
    • In-stock
      2-Fluoro-4-iodobenzoic acid|CS-W002999
      124700-40-9

    References

    • Rausis, Thierry; Schlosser, Manfred European Journal of Organic Chemistry, 2002 , # 19 p. 3351 - 3358
  • Route3
    • null|null
      462-06-6
    • ~%
    • In-stock
      2-Fluoro-4-iodobenzoic acid|CS-W002999
      124700-40-9

    References

    • European Journal of Organic Chemistry, , # 19 p. 3351 - 3358

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.1285
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   1

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