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CS-W001157 4
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3-Methylazetidin-3-ol hydrochloride

  • CAS No. 124668-46-8

  • Cat. No. CS-0007720
  • Purity≥97%
  • MDL No.MFCD11100994

*For research and further manufacturing use only, not for direct human use.

3-Methylazetidin-3-ol hydrochloride|CS-0007720

Structure of 124668-46-8

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General Information

  • CAS No. 124668-46-8
  • Cat. No. CS-0007720
  • Purity ≥97%
  • MDL No. MFCD11100994
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₀ClNO
  • Molecular Weight 123.58
  • Synonym(s) None
  • SMILES OC1(C)CNC1.Cl

Description

3-Methylazetidin-3-ol hydrochloride is a bench-stable, moisture-tolerant heterocyclic building block featuring a tertiary alcohol within a strained four-membered ring. This scaffold integrates readily into medicinal chemistry libraries, where the hydroxyl group enables direct derivatization and the protonated amine enhances solubility in aqueous systems.

Application

3-Methylazetidin-3-ol hydrochloride serves as a valuable synthetic building block for saturated nitrogen heterocycles, offering a strained four-membered ring with a pendant hydroxyl group. The compound exhibits good bench stability and facilitates efficient functionalization at the hydroxyl site, enabling straightforward derivatization for medicinal chemistry applications. Its defined stereochemistry and solubility profile support reliable incorporation into diverse coupling and cyclization sequences.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   32.26
  • LogP   -0.2376
  • H_Acceptors   2
  • H_Donors   2
  • Rotatable_Bonds   0

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