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CS-W001157 4
Total: USD 88.00

Bis-PEG8-acid

  • CAS No. 1246189-43-4

  • Cat. No. CS-0107999
  • Purity≥97%
  • MDL No.MFCD29917781

*For research and further manufacturing use only, not for direct human use.

Bis-PEG8-acid|CS-0107999

Structure of 1246189-43-4

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General Information

  • CAS No. 1246189-43-4
  • Cat. No. CS-0107999
  • Purity ≥97%
  • MDL No. MFCD29917781
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₃₈O₁₂
  • Molecular Weight 470.51
  • Synonym(s) None
  • SMILES O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O

Description

Bis-PEG8-acid features two PEG8 chains flanking a central dicarboxylic acid core, offering enhanced solubility and biocompatibility. This structure enables efficient conjugation in aqueous media, facilitating use in drug delivery systems and bioconjugate synthesis under standard conditions.

Application

Bis-PEG8-acid serves as a versatile, water-soluble linker for the construction of bioconjugates and functionalized polymers. Its two terminal carboxylic acid groups enable efficient coupling to amine-containing biomolecules or surfaces via standard amide bond formation. The PEG8 spacers provide enhanced solubility, reduced non-specific binding, and improved pharmacokinetic properties in biological applications. This bifunctional reagent offers excellent bench stability, ease of purification, and compatibility with diverse reaction conditions in synthetic and medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   148.44
  • LogP   0.0686
  • H_Acceptors   10
  • H_Donors   2
  • Rotatable_Bonds   27

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