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CS-W001157 4
Total: USD 88.00

(3-Methyl-1H-indazol-6-yl)boronic acid

  • CAS No. 1245816-26-5

  • Cat. No. CS-0006097
  • Purity≥96%
  • MDL No.MFCD11044596

*For research and further manufacturing use only, not for direct human use.

(3-Methyl-1H-indazol-6-yl)boronic acid|CS-0006097

Structure of 1245816-26-5

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General Information

  • CAS No. 1245816-26-5
  • Cat. No. CS-0006097
  • Purity ≥96%
  • MDL No. MFCD11044596
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₉BN₂O₂
  • Molecular Weight 175.98
  • Synonym(s) 3-Methyl-1H-indazole-6-boronic acid
  • SMILES OB(C1=CC2=C(C=C1)C(C)=NN2)O

Description

(3-Methyl-1H-indazol-6-yl)boronic acid features a boronate moiety attached to a sterically accessible indazole scaffold, enabling efficient Suzuki-Miyaura coupling under mild conditions. This bench-stable reagent integrates readily into complex heterocyclic architectures, delivering high functional group tolerance and predictable reaction outcomes in medicinal chemistry applications.

Application

(3-Methyl-1H-indazol-6-yl)boronic acid serves as a versatile building block in Suzuki-Miyaura cross-coupling reactions, enabling efficient construction of biaryl scaffolds under mild conditions. Its stability, ease of handling, and compatibility with diverse functional groups make it ideal for medicinal chemistry applications and the synthesis of heterocyclic compounds. The boronic acid moiety facilitates reliable coupling with aryl halides and pseudohalides, supporting rapid library generation and scale-up.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   69.14
  • LogP   -0.44888
  • H_Acceptors   3
  • H_Donors   3
  • Rotatable_Bonds   1

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