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Structure of 124432-71-9
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5-Fluoro-6-methoxy-3-pyridinol features a pyridinol core with strategically positioned fluorine and methoxy groups, delivering enhanced electron-withdrawing character and improved solubility. This combination enables efficient incorporation into bioactive scaffolds, particularly in kinase inhibitors and pharmaceutical intermediates, where metabolic stability and target affinity are critical.
5-Fluoro-6-methoxy-3-pyridinol serves as a versatile building block in medicinal chemistry, enabling the synthesis of fluorinated heterocyclic scaffolds. Its ortho-substituted pyridinol core offers enhanced metabolic stability and tunable polarity, while the methoxy group facilitates further functionalization via Suzuki-Miyaura or Ullmann coupling. The molecule exhibits excellent bench stability and compatibility with standard synthetic protocols, making it well-suited for iterative library synthesis and API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362-P405-P501
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Lot numbers can be found on the outside label of a product: