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Structure of 1239462-77-1
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5-Bromo-7-(trifluoromethyl)quinoline features a sterically hindered trifluoromethyl group at the 7-position, enhancing metabolic stability and electron-withdrawing character. This quinoline scaffold integrates seamlessly into transition metal-catalyzed cross-coupling reactions, enabling efficient access to complex heterocyclic architectures in medicinal chemistry and materials science.
5-Bromo-7-(trifluoromethyl)quinoline serves as a versatile building block in medicinal chemistry and materials science, enabling palladium-catalyzed cross-coupling reactions due to its well-defined reactivity at the bromo position. The trifluoromethyl group enhances metabolic stability and lipophilicity, while the quinoline core provides a rigid, planar scaffold suitable for targeted molecular design. Bench-stable and compatible with standard purification protocols, it facilitates efficient synthesis of complex heterocyclic architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: