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Structure of 1239017-80-1
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This photoreactive ester features a 3-methyl-3H-diazirine ring that enables efficient, irreversible crosslinking upon UV activation. The dioxopyrrolidinyl group enhances leaving group stability and reactivity, facilitating conjugation to primary amines under mild conditions. Designed for site-specific labeling in biomolecular studies, this compound delivers high functionalization yields with minimal background.
2,5-Dioxopyrrolidin-1-yl 3-(3-methyl-3H-diazirin-1-yl)propanoate serves as a stable, bench-compatible activated ester for site-specific photoaffinity labeling. The methyl-substituted diazirine moiety enables efficient UV-induced insertion into C–H and N–H bonds, facilitating covalent crosslinking of transient biomolecular interactions. Its functional group tolerance and compatibility with standard peptide and small-molecule conjugation protocols make it a practical tool for target identification in chemical biology workflows.
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GHS Pictogram :
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GHS No : GHS02,GHS07
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Signal Word : Danger
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UN#: 1325
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Class : 4.1
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Packing Group : Ⅱ
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Hazard Statements : H228-H315-H319
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Precautionary Statements : P210-P240-P241-P264-P280-P302+P352-P362+P364-P370+P378
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Lot numbers can be found on the outside label of a product: