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CS-W001157 4
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3-(Azetidin-3-yl)pyridine dihydrochloride

  • CAS No. 1236791-61-9

  • Cat. No. CS-W021764
  • Purity≥98%
  • MDL No.MFCD20527356

*For research and further manufacturing use only, not for direct human use.

3-(Azetidin-3-yl)pyridine dihydrochloride|CS-W021764

Structure of 1236791-61-9

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General Information

  • CAS No. 1236791-61-9
  • Cat. No. CS-W021764
  • Purity ≥98%
  • MDL No. MFCD20527356
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂Cl₂N₂
  • Molecular Weight 207.10
  • Synonym(s) 3-(3-azetidinyl)Pyridine dihydrochloride cas
  • SMILES C1(C2=CC=CN=C2)CNC1.Cl.Cl

Description

3-(Azetidin-3-yl)pyridine dihydrochloride features a pyridine core linked to an azetidine ring, delivering enhanced solubility and improved metabolic stability. The dihydrochloride salt form ensures excellent crystallinity and handling ease, facilitating integration into medicinal chemistry workflows. This compound serves as a key scaffold in bioactive molecule design.

Application

3-(Azetidin-3-yl)pyridine dihydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient construction of nitrogen-containing heterocycles. The azetidine moiety provides enhanced metabolic stability and improved solubility, while the pyridine ring offers a robust platform for transition-metal-catalyzed couplings. Its dihydrochloride salt form enhances bench stability and simplifies purification, facilitating integration into multi-step syntheses of API candidates and functionalized scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   24.92
  • LogP   1.612
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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