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Structure of 123654-26-2
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This benzofuran derivative features a chloro substituent at the 5-position and an amino group at the 4-position, enhancing its reactivity in coupling reactions. The carboxylic acid moiety enables direct conjugation or derivatization, while the dihydrobenzofuran core offers rigidity and metabolic stability. Suitable for pharmaceutical intermediates and bioconjugate synthesis under standard conditions.
4-Amino-5-chloro-2,3-dihydro-1-benzofuran-7-carboxylic acid serves as a versatile building block for medicinal chemistry campaigns, enabling the construction of bioactive heterocycles via standard amide coupling, Suzuki-Miyaura, and electrophilic substitution reactions. The molecule exhibits good bench stability, tolerates diverse functional groups, and facilitates efficient purification—making it well-suited for lead optimization and API intermediate synthesis.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: