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Structure of 1236357-65-5
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Methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate is a bench-stable cyclobutane derivative bearing a para-bromophenyl group and an ester-functionalized ring. This structure enables direct incorporation into synthetic sequences requiring rigid, electron-deficient aromatic coupling partners. The bromine moiety facilitates subsequent cross-coupling reactions, while the cyclobutane core provides conformational constraint ideal for medicinal chemistry scaffolds.
Methyl 1-(4-bromophenyl)cyclobutane-1-carboxylate serves as a versatile building block for the synthesis of functionalized cyclobutane scaffolds. The bromoaryl group enables palladium-catalyzed cross-coupling reactions, while the ester functionality supports hydrolysis and derivatization. Bench-stable and readily purified by column chromatography, it facilitates efficient access to biologically relevant motifs in medicinal chemistry and materials science.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: