6-Fluoroimidazo[1,2-a]pyridin-3-amine

Name: 6-Fluoroimidazo[1,2-a]pyridin-3-amine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1235993-31-3
Cat. No. CS-0139895
Purity≥98%
MDL No.None

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
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Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
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6-Fluoroimidazo[1,2-a]pyridin-3-amine|CS-0139895

Structure of 1235993-31-3

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Description

6-Fluoroimidazo[1,2-a]pyridin-3-amine features a fluorinated imidazopyridine core with a primary amine at the 3-position, enabling direct conjugation in medicinal chemistry. The electron-deficient heterocycle enhances binding affinity in kinase inhibitors and other target-directed scaffolds. This bench-stable compound integrates readily into diverse synthetic pathways under standard conditions.

Application

6-Fluoroimidazo[1,2-a]pyridin-3-amine serves as a versatile heterocyclic building block for medicinal chemistry and catalytic synthesis. Its fluorinated imidazopyridine core enables robust coupling reactions and functions as a key scaffold in kinase inhibitor development. The molecule exhibits good bench stability, facilitates efficient derivatization via nucleophilic substitution, and demonstrates favorable functional group tolerance in standard synthetic workflows.

General Information

CAS No. 1235993-31-3
Cat. No. CS-0139895
Purity ≥98%
MDL No. None
Storage 4°C, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₇H₆FN₃
Molecular Weight 151.14
Synonym(s) 6-Fluoro-imidazo[1,2-a]pyridin-3-ylamine
SMILES NC1=CN=C2C=CC(F)=CN21

Computational Chemistry Data

TPSA 43.32
LogP 1.0556
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 0

Safety Information

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GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Other Classifications

Building Blocks Functional Group Fluoride

Building Blocks Skeleton Aromatic heterocycle compounds Imidazole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

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6-Fluoroimidazo[1,2-a]pyridin-3-amine

CAS No. 1235993-31-3

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