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Structure of 1235451-38-3
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tert-Butyl ((5-bromopyrimidin-2-yl)methyl)carbamate delivers a brominated pyrimidine scaffold with a readily cleavable carbamate protecting group. This reagent enables direct functionalization at the 5-position of pyrimidine rings, facilitating late-stage diversification in medicinal chemistry. The tert-butyl carbamate moiety ensures stability during synthesis and purification, while the bromine atom provides a reactive handle for cross-coupling transformations.
tert-Butyl ((5-bromopyrimidin-2-yl)methyl)carbamate serves as a versatile building block for the synthesis of brominated pyrimidine derivatives, enabling straightforward functionalization at the 5-position. The Boc-protected amine facilitates orthogonal handling in multi-step sequences, while the bromide acts as a reliable coupling handle in palladium-catalyzed transformations. Its bench stability and compatibility with standard reaction conditions make it ideal for medicinal chemistry and process development workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: