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Structure of 1233369-41-9
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N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S,2S)-2-(dimethylamino)-1,2-diphenylethyl]thiourea features a sterically hindered thiourea core flanked by electron-deficient aryl and chiral diphenylethyl moieties. This configuration enables strong hydrogen-bonding interactions and enantioselective recognition in supramolecular systems. The trifluoromethyl groups enhance lipophilicity and metabolic stability, while the (1S,2S)-configured amine imparts defined stereochemistry crucial for asymmetric synthesis applications.
N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(1S,2S)-2-(dimethylamino)-1,2-diphenylethyl]thiourea serves as a versatile scaffold in medicinal chemistry, enabling the construction of bioactive heterocycles through standard coupling and cyclization protocols. Its trifluoromethylated aryl group enhances metabolic stability and lipophilicity, while the chiral diphenylethyl moiety provides steric control in asymmetric synthesis. The thiourea functionality offers strong hydrogen-bonding capacity and compatibility with diverse functional groups, facilitating purification and crystallization. This compound exhibits bench stability and is well-suited for high-throughput screening campaigns and lead optimization workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: