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CS-W001157 4
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4,5,6,7-Tetrahydro-[1,2,3]triazolo[1,5-a]pyrazine

  • CAS No. 123291-54-3

  • Cat. No. CS-0199611
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

4,5,6,7-Tetrahydro-[1,2,3]triazolo[1,5-a]pyrazine|CS-0199611

Structure of 123291-54-3

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General Information

  • CAS No. 123291-54-3
  • Cat. No. CS-0199611
  • Purity ≥98%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₅H₈N₄
  • Molecular Weight 124.14
  • Synonym(s) 4,5,6,7-Tetrahydro-1,2,3-triazolo[1,5-A]pyrazine
  • SMILES C1CN2C(=CN=N2)CN1

Description

4,5,6,7-Tetrahydro-[1,2,3]triazolo[1,5-a]pyrazine is a nitrogen-rich heterocyclic scaffold featuring a fully saturated triazolopyrazine core. This stable, electron-deficient framework integrates seamlessly into medicinal chemistry libraries and serves as a key structural motif in kinase inhibitors and CNS-targeted therapeutics.

Application

4,5,6,7-Tetrahydro-[1,2,3]triazolo[1,5-a]pyrazine serves as a versatile heterocyclic scaffold in medicinal chemistry, enabling efficient access to bioactive compounds through standard functionalization at the pyrazine core. Its stability under physiological conditions and compatibility with common coupling reactions facilitate downstream derivatization. The molecule functions as a key building block for targeted synthesis of potential kinase inhibitors and CNS-active agents, offering robust reactivity and predictable transformation pathways in multistep organic syntheses.

Safety Information

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GHS Pictogram :
GHS No : GHS05
Signal Word : Danger
UN#: 1759
Class : 8
Packing Group : Ⅲ
Hazard Statements : H314
Precautionary Statements : P260-P264-P280-P301+P330+P331-P303+P361+P353-P363-P304+P340-P310-P305+P351+P338-P405-P501

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Computational Chemistry Data

  • TPSA   42.74
  • LogP   -0.6187
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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