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Structure of 123254-58-0
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(R)-2-((tert-Butoxycarbonyl)amino)-2-methylbutanoic acid is a chiral building block featuring a sterically hindered α-methyl group and a bench-stable Boc-protected amine. This configuration enables direct incorporation into peptide synthesis workflows without racemization, delivering high fidelity in complex sequence assembly.
(R)-2-((tert-Butoxycarbonyl)amino)-2-methylbutanoic acid serves as a valuable chiral building block in peptide synthesis and medicinal chemistry. Its tert-butyl carbamate (Boc) group provides robust protection of the amine, enabling selective deprotection under mild acidic conditions. The sterically hindered α-methyl group enhances stability and reduces racemization during coupling reactions. This compound facilitates efficient access to complex peptidomimetics and bioactive scaffolds through standard amide bond formation protocols.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: