Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline

  • CAS No. 1231892-80-0

  • Cat. No. CS-0135498
  • Purity≥97%
  • MDL No.MFCD18383607

*For research and further manufacturing use only, not for direct human use.

2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline|CS-0135498

Structure of 1231892-80-0

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 1231892-80-0
  • Cat. No. CS-0135498
  • Purity ≥97%
  • MDL No. MFCD18383607
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₂H₁₇BFNO₂
  • Molecular Weight 237.08
  • Synonym(s) 3-AMINO-2-FLUOROPHENYLBORONIC ACID PINACOL ESTER
  • SMILES NC1=CC=CC(B2OC(C)(C)C(C)(C)O2)=C1F

Description

This boronate-functional aniline integrates seamlessly into Suzuki-Miyaura cross-coupling reactions, offering enhanced stability and moisture tolerance. The ortho-fluoro substituent enables selective activation, while the tetramethyl-substituted dioxaborolane group ensures efficient coupling under mild conditions.

Application

2-Fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)aniline serves as a versatile boron-containing building block in Suzuki-Miyaura cross-coupling reactions. The boronate ester group enables efficient C–C bond formation under mild conditions, while the ortho-fluoro substituent provides enhanced stability and orthogonal reactivity. This compound exhibits excellent bench stability, straightforward purification, and broad functional group tolerance, making it ideal for constructing complex aromatic scaffolds in medicinal chemistry and materials science applications.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   44.48
  • LogP   1.7071
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 1231892-80-0 sigma1231892-80-0 manufacturer1231892-80-0 price1231892-80-0 structure1231892-80-0 SDSbuy 1231892-80-01231892-80-0 supplier1231892-80-0 uses1231892-80-0 molecular weightprice of 1231892-80-01231892-80-0 chemical name formula of 1231892-80-0
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label