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Structure of 1231761-23-1
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1-Chloroisoquinoline-5-carbonitrile features a chlorine atom at the 1-position and a nitrile group at the 5-position of the isoquinoline scaffold. This electron-deficient heterocycle integrates readily into cross-coupling reactions, serving as a pivotal building block for pharmaceutical intermediates and functional materials.
1-Chloroisoquinoline-5-carbonitrile serves as a versatile building block in medicinal chemistry, enabling direct functionalization at the C5 position via nucleophilic substitution. The chloro group exhibits high reactivity toward amines, thiols, and other nucleophiles under mild conditions, while the nitrile moiety provides compatibility with standard transformations such as hydrolysis or reduction. Its bench-stable nature and orthogonal reactivity profile facilitate efficient synthesis of isoquinoline-based scaffolds for drug discovery applications.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: