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CS-W001157 4
Total: USD 88.00

4-(4-Iodo-1H-pyrazol-1-yl)piperidine

  • CAS No. 1229457-94-6

  • Cat. No. CS-0038566
  • Molecule weightNone
  • Purity≥95%
  • MDL No.MFCD16622252

*For research and further manufacturing use only, not for direct human use.

4-(4-Iodo-1H-pyrazol-1-yl)piperidine|CS-0038566

Structure of 1229457-94-6

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General Information

  • CAS No. 1229457-94-6
  • Cat. No. CS-0038566
  • Purity ≥95%
  • MDL No. MFCD16622252
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₁₂IN₃
  • Molecular Weight None
  • Synonym(s) 4-(4-iodo-pyrazol-1-yl)piperidine
  • SMILES C1CNCCC1N2C=C(C=N2)I

Description

4-(4-Iodo-1H-pyrazol-1-yl)piperidine features a pyrazole ring bearing a reactive iodine substituent, enabling efficient cross-coupling transformations. The piperidine moiety provides a basic, lipophilic scaffold ideal for medicinal chemistry applications. This compound serves as a versatile building block in the synthesis of bioactive molecules and functional materials.

Application

4-(4-Iodo-1H-pyrazol-1-yl)piperidine serves as a versatile building block for constructing bioactive heterocycles, enabling efficient late-stage functionalization via palladium-catalyzed cross-coupling reactions. The iodopyrazole moiety exhibits excellent stability under standard synthetic conditions and facilitates modular assembly of complex scaffolds. Its compatibility with diverse reaction partners and ease of purification make it well-suited for medicinal chemistry campaigns and process development in API synthesis.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H301-H317-H318
Precautionary Statements : P261-P264-P270-P272-P280-P302+P352-P330-P338-P362-P405-P501

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   1.4122
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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