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1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine dihydrochloride

  • CAS No. 1228878-69-0

  • Cat. No. CS-W006892
  • Purity≥95%
  • MDL No.MFCD09028172

*For research and further manufacturing use only, not for direct human use.

1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine dihydrochloride|CS-W006892

Structure of 1228878-69-0

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General Information

  • CAS No. 1228878-69-0
  • Cat. No. CS-W006892
  • Purity ≥95%
  • MDL No. MFCD09028172
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃Cl₂N₃
  • Molecular Weight 210.10
  • Synonym(s) 1-methyl-4,5,6,7-tetrahydropyrazolo[3,4-c]pyridine
  • SMILES CN1C2=C(C=N1)CCNC2.Cl.Cl

Description

This tetrahydro-pyrazolopyridine dihydrochloride delivers a rigid, electron-rich heterocyclic scaffold ideal for medicinal chemistry. The fused ring system enhances metabolic stability while the protonated nitrogen improves solubility and facilitates salt formation. This compound integrates readily into drug discovery campaigns requiring bioavailable, planar core structures.

Application

1-Methyl-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine dihydrochloride serves as a versatile heterocyclic building block for medicinal chemistry and process development. Its saturated pyrazolopyridine core exhibits excellent bench stability and functional group tolerance, enabling efficient incorporation into diverse molecular architectures. The dihydrochloride salt form enhances solubility and crystallinity, facilitating purification and handling in standard synthetic workflows. This compound functions effectively in transition metal-catalyzed couplings and nucleophilic substitution reactions, supporting the construction of complex API-relevant scaffolds.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   29.85
  • LogP   0.9094
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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