5-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde

Name: 5-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1227603-42-0
Cat. No. CS-0157349
Purity≥96%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

5-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde|CS-0157349

Structure of 1227603-42-0

Size

Price

Quantity

* Please select Quantity before adding items.

Description

5-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde features a brominated dihydropyridine core with orthogonal functional groups: a carbonyl at C2 and an aldehyde at C3. This electron-deficient scaffold enables direct coupling in heterocyclic synthesis, serving as a key intermediate for bioactive pyridine derivatives. The molecule exhibits bench-stable handling under standard conditions.

Application

5-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde serves as a versatile building block in heterocyclic synthesis, enabling efficient access to substituted pyridine derivatives via Pd-catalyzed cross-coupling and nucleophilic addition reactions. Its dual functionality—branched bromide and aldehyde groups—facilitates sequential transformations under mild conditions, while the enone system supports conjugate addition pathways. The compound exhibits bench stability and compatibility with common protecting groups, making it well-suited for iterative synthetic strategies in medicinal chemistry and process development.

General Information

CAS No. 1227603-42-0
Cat. No. CS-0157349
Purity ≥96%
MDL No. None
Storage 4°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₄BrNO₂
Molecular Weight 202.01
Synonym(s) None
SMILES C1=C(C=O)C(=NC=C1Br)O

Computational Chemistry Data

TPSA 50.19
LogP 1.3622
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Other Classifications

Building Blocks Functional Group Aldehyde

Building Blocks Functional Group Bromide

Building Blocks Skeleton Aromatic heterocycle compounds Pyridine compounds

Key Words

1227603-42-0 sigma1227603-42-0 manufacturer1227603-42-0 price1227603-42-0 structure1227603-42-0 SDSbuy 1227603-42-01227603-42-0 supplier1227603-42-0 uses1227603-42-0 molecular weightprice of 1227603-42-01227603-42-0 chemical name formula of 1227603-42-0

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

5-Bromo-2-oxo-1,2-dihydropyridine-3-carbaldehyde

CAS No. 1227603-42-0

Recommended Products