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CS-W001157 4
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3-Methylimidazo[1,2-a]pyridine-2-carboxylic acid

  • CAS No. 1227268-77-0

  • Cat. No. CS-0046957
  • Purity≥97%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

3-Methylimidazo[1,2-a]pyridine-2-carboxylic acid|CS-0046957

Structure of 1227268-77-0

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General Information

  • CAS No. 1227268-77-0
  • Cat. No. CS-0046957
  • Purity ≥97%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₈N₂O₂
  • Molecular Weight 176.17
  • Synonym(s) 3-Methyl-imidazo[1,2-a]pyridine-2-carboxylic acid
  • SMILES O=C(C1=C(N2C=CC=CC2=N1)C)O

Description

This heterocyclic carboxylic acid features a fused imidazo[1,2-a]pyridine core with a methyl substituent at the 3-position, delivering enhanced solubility and stability under standard conditions. The carboxylate group enables direct conjugation in medicinal chemistry scaffolds, while the electron-deficient aromatic system supports efficient coupling reactions.

Application

3-Methylimidazo[1,2-a]pyridine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and catalytic system development. Its fused imidazo[1,2-a]pyridine core provides enhanced rigidity and π-conjugation, enabling robust interactions in target binding. The carboxylic acid group facilitates direct derivatization or salt formation, supporting purification and solubility modulation. Bench-stable and compatible with standard coupling reactions, it functions effectively in the synthesis of advanced scaffolds and functional materials.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   54.6
  • LogP   1.34092
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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