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Structure of 1227160-18-0
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1-Bromo-4-(1-(trifluoromethyl)cyclopropyl)benzene features a trifluoromethyl-cyclopropyl substituent that imparts enhanced metabolic stability and lipophilicity, making it valuable for medicinal chemistry. The bromine handle enables efficient cross-coupling reactions under standard conditions, facilitating the rapid assembly of complex aryl architectures in drug discovery pipelines.
1-Bromo-4-(1-(trifluoromethyl)cyclopropyl)benzene serves as a versatile aryl halide building block for Suzuki-Miyaura and Negishi coupling reactions, enabling efficient construction of biaryl scaffolds. The trifluoromethylcyclopropyl group imparts enhanced metabolic stability and lipophilicity, making it valuable in medicinal chemistry. Its bench-stable nature and compatibility with standard cross-coupling conditions facilitate reliable synthesis of complex functionalized arenes.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: